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About Sickle Cell Disorder

IBSCF > Sickle Cell Disorder

Sickle Cell Disorder is a hereditary haemoglobin disorder which occurs when a person inherits two abnormal copies of the haemoglobin gene, one from each parent. This is a lifelong ailment characterized by premature breakdown of rigidly sickled red blood cells causing, in the case of HbSS, constant anaemia and occlusion of small blood vessels, which is believed leads to pain crises and other manifestations.

About 2% of all babies born to Nigerian parents have sickle cell anaemia. Two per hundred births translates to over 150,000 births annually of children with sickle cell anaemia which makes us the country with the highest burden of sickle cell disorder in the world. However, survival of these babies beyond childhood is largely dependent on their access to good basic health care and as most of these children are born into poor underprivileged families, they hardly survive childhood. On the other hand, the survival of those with access to good health care at every stage of life is steadily improving.

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